Flexible PET/ITO electrode array for implantable biomedical applications.
Identifieur interne : 001420 ( Main/Exploration ); précédent : 001419; suivant : 001421Flexible PET/ITO electrode array for implantable biomedical applications.
Auteurs : RBID : pubmed:22254942English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Polyethylene Glycols, Tin Compounds.
- Dielectric Spectroscopy, Electrodes, Implanted.
Abstract
Flexible PET/ITO (PolyEthylene Terephthalate/ Indium Tin Oxide) implantable electrode array for spinal cord stimulation and retina prosthesis have been developed. The electrode array is fabricated on a thin PET/ITO substrate and encapsulated with insulating material, SU-8. The PET substrate made electrodes flexible so that they could shape to contoured tissues. A layer of gold on the stimulation sites served to reduce the electrode/tissue interface impedance. Prototypes of 1 × 8 and 3 × 8 electrode arrays are fabricated for monophasic and biphasic stimulation of spinal cord respectively. The exposed electrode dimensions are 3 mm² for monophasic and 6 mm² for biphasic stimulation with 100 μm of interconnection paths. The prototype of 4 × 4 electrode arrays were also fabricated with the same process for retinal prosthesis with exposed electrode diameter of 125 μm. To verify the functionality of the subdural electrodes, the electrochemical impedance spectroscopy was measured. The electrode/tissue impedance was 500 Ω at 1KHz for 3 mm² area.
DOI: 10.1109/IEMBS.2011.6090794
PubMed: 22254942
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Le document en format XML
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<author><name sortKey="Ahani, Asieh" uniqKey="Ahani A">Asieh Ahani</name>
<affiliation wicri:level="1"><nlm:affiliation>Integrated Circuits and Systems Laboratory, Electrical & Computer Eng Dept, KN Toosi University of Technology, Tehran, Iran. saadatileila@ee.kntu.ac.ir</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Integrated Circuits and Systems Laboratory, Electrical & Computer Eng Dept, KN Toosi University of Technology, Tehran</wicri:regionArea>
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<author><name sortKey="Saadati Fard, Laila" uniqKey="Saadati Fard L">Laila Saadati-Fard</name>
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<author><name sortKey="Sodagar, Amir M" uniqKey="Sodagar A">Amir M Sodagar</name>
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<author><name sortKey="Boroumad, Farhad A" uniqKey="Boroumad F">Farhad A Boroumad</name>
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<term>Electrodes, Implanted</term>
<term>Polyethylene Glycols (chemistry)</term>
<term>Tin Compounds (chemistry)</term>
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<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Polyethylene Glycols</term>
<term>Tin Compounds</term>
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<front><div type="abstract" xml:lang="en">Flexible PET/ITO (PolyEthylene Terephthalate/ Indium Tin Oxide) implantable electrode array for spinal cord stimulation and retina prosthesis have been developed. The electrode array is fabricated on a thin PET/ITO substrate and encapsulated with insulating material, SU-8. The PET substrate made electrodes flexible so that they could shape to contoured tissues. A layer of gold on the stimulation sites served to reduce the electrode/tissue interface impedance. Prototypes of 1 × 8 and 3 × 8 electrode arrays are fabricated for monophasic and biphasic stimulation of spinal cord respectively. The exposed electrode dimensions are 3 mm² for monophasic and 6 mm² for biphasic stimulation with 100 μm of interconnection paths. The prototype of 4 × 4 electrode arrays were also fabricated with the same process for retinal prosthesis with exposed electrode diameter of 125 μm. To verify the functionality of the subdural electrodes, the electrochemical impedance spectroscopy was measured. The electrode/tissue impedance was 500 Ω at 1KHz for 3 mm² area.</div>
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<Title>Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference</Title>
<ISOAbbreviation>Conf Proc IEEE Eng Med Biol Soc</ISOAbbreviation>
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<ArticleTitle>Flexible PET/ITO electrode array for implantable biomedical applications.</ArticleTitle>
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<Abstract><AbstractText>Flexible PET/ITO (PolyEthylene Terephthalate/ Indium Tin Oxide) implantable electrode array for spinal cord stimulation and retina prosthesis have been developed. The electrode array is fabricated on a thin PET/ITO substrate and encapsulated with insulating material, SU-8. The PET substrate made electrodes flexible so that they could shape to contoured tissues. A layer of gold on the stimulation sites served to reduce the electrode/tissue interface impedance. Prototypes of 1 × 8 and 3 × 8 electrode arrays are fabricated for monophasic and biphasic stimulation of spinal cord respectively. The exposed electrode dimensions are 3 mm² for monophasic and 6 mm² for biphasic stimulation with 100 μm of interconnection paths. The prototype of 4 × 4 electrode arrays were also fabricated with the same process for retinal prosthesis with exposed electrode diameter of 125 μm. To verify the functionality of the subdural electrodes, the electrochemical impedance spectroscopy was measured. The electrode/tissue impedance was 500 Ω at 1KHz for 3 mm² area.</AbstractText>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ahani</LastName>
<ForeName>Asieh</ForeName>
<Initials>A</Initials>
<Affiliation>Integrated Circuits and Systems Laboratory, Electrical & Computer Eng Dept, KN Toosi University of Technology, Tehran, Iran. saadatileila@ee.kntu.ac.ir</Affiliation>
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<Author ValidYN="Y"><LastName>Sodagar</LastName>
<ForeName>Amir M</ForeName>
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<Chemical><RegistryNumber>71243-84-0</RegistryNumber>
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